Bone contact, growth, and density around immediately loaded implants in the mandible of mini pigs
Identifieur interne : 008054 ( Main/Exploration ); précédent : 008053; suivant : 008055Bone contact, growth, and density around immediately loaded implants in the mandible of mini pigs
Auteurs : Emeka Nkenke [Allemagne] ; Bernhard Lehner [Allemagne] ; Konstanze Weinzierl [Allemagne] ; Ulf Thams [Allemagne] ; Jörg Neugebauer [Allemagne] ; Helmut Steveling [Allemagne] ; Martin Radespiel-Tröger [Allemagne] ; Friedrich Wilhelm Neukam [Allemagne]Source :
- Clinical Oral Implants Research [ 0905-7161 ] ; 2003-05.
Descripteurs français
- KwdFr :
- Animaux, Calcification physiologique (physiologie), Cicatrisation de plaie, Colorants fluorescents, Densité osseuse (physiologie), Implants dentaires, Mandibule (anatomopathologie), Mise en charge, Mâchoire partiellement édentée (), Mâchoire partiellement édentée (anatomopathologie), Ostéo-intégration, Ostéogenèse (physiologie), Porc miniature, Propriétés de surface, Prothèse dentaire implanto-portée, Prothèse dentaire partielle provisoire, Prothèse partielle fixe, Statistique non paramétrique, Suidae, Échec de restauration dentaire.
- MESH :
- anatomopathologie : Mandibule, Mâchoire partiellement édentée.
- physiologie : Calcification physiologique, Densité osseuse, Ostéogenèse.
- Wicri :
- topic : Animaux, Cicatrisation de plaie, Colorants fluorescents, Implants dentaires, Mise en charge, Mâchoire partiellement édentée, Ostéo-intégration, Porc miniature, Propriétés de surface, Prothèse dentaire implanto-portée, Prothèse dentaire partielle provisoire, Prothèse partielle fixe, Statistique non paramétrique, Suidae, Titane, Échec de restauration dentaire.
English descriptors
- KwdEn :
- Animals, Apical thread, Apposition, Beagle dogs, Bmar, Bmar jours, Body weight, Bone Density (physiology), Bone area, Bone density, Bone formation, Bone growth, Bone mineral apposition rate, Bone remodelling, Brunski, Calcification, Physiologic (physiology), Cargados, Case reports, Clin, Current literature, Days bmar, Days pbmar, Dental Implants, Dental Prosthesis, Implant-Supported, Dental Restoration Failure, Dental implantology, Dental implants, Dentistry, Denture, Partial, Fixed, Denture, Partial, Temporary, Edentulous, Edentulous mandible, Experimental animal trials, Fluorescent Dyes, Friadent gmbh, General anaesthesia, Gmbh, Healing period, Histological, Histomorphometric, Histomorphometric analysis, Immediate loading, Impl, Implant, Implant placement, Implant success, Implantes, Implants research, International journal, Interthread bone area, Jaw, Edentulous, Partially (pathology), Jaw, Edentulous, Partially (surgery), Jours, Mandible, Mandible (pathology), Maxillofacial, Maxillofacial implants, Maxillofacial surgery, Mini, Mini pigs, Nemark, Nemark implants, Nkenke, Observation period, Oral impl, Osseointegration, Osteogenesis (physiology), Pbmar, Periodontology, Piattelli, Placement torque value, Present study, Primary stability, Prosthetic dentistry, Provisional restoration, Provisional restorations, Remodelling, Restorative dentistry, Rigid splinting, Rztliche implantologie, Screw implants, Splinting, Statistics, Nonparametric, Surface Properties, Swine, Swine, Miniature, Temporary abutment caps, Titanium, Titanium implants, Uncontrolled masticatory forces, Uorescence, Uorescence labelling, Uorescent dyes, Weight-Bearing, Wound Healing, Zeiss gmbh, Zubery.
- MESH :
- chemical : Dental Implants, Fluorescent Dyes.
- pathology : Jaw, Edentulous, Partially, Mandible.
- physiology : Bone Density, Calcification, Physiologic, Osteogenesis.
- surgery : Jaw, Edentulous, Partially.
- Teeft :
- Animals, Apical thread, Apposition, Beagle dogs, Bmar, Bmar jours, Body weight, Bone area, Bone density, Bone formation, Bone growth, Bone mineral apposition rate, Bone remodelling, Brunski, Cargados, Case reports, Clin, Current literature, Days bmar, Days pbmar, Dental Prosthesis, Implant-Supported, Dental Restoration Failure, Dental implantology, Dental implants, Dentistry, Denture, Partial, Fixed, Denture, Partial, Temporary, Edentulous, Edentulous mandible, Experimental animal trials, Friadent gmbh, General anaesthesia, Gmbh, Healing period, Histological, Histomorphometric, Histomorphometric analysis, Immediate loading, Impl, Implant, Implant placement, Implant success, Implantes, Implants research, International journal, Interthread bone area, Jours, Mandible, Maxillofacial, Maxillofacial implants, Maxillofacial surgery, Mini, Mini pigs, Nemark, Nemark implants, Nkenke, Observation period, Oral impl, Osseointegration, Pbmar, Periodontology, Piattelli, Placement torque value, Present study, Primary stability, Prosthetic dentistry, Provisional restoration, Provisional restorations, Remodelling, Restorative dentistry, Rigid splinting, Rztliche implantologie, Screw implants, Splinting, Statistics, Nonparametric, Surface Properties, Swine, Swine, Miniature, Temporary abutment caps, Titanium, Titanium implants, Uncontrolled masticatory forces, Uorescence, Uorescence labelling, Uorescent dyes, Weight-Bearing, Wound Healing, Zeiss gmbh, Zubery.
Abstract
Abstract: The aim of the study was to compare the bone mineral apposition rate (BMAR) of immediately loaded implants with an unloaded control during the early healing phase in the partially edentulous mandible. In seven mini pigs, three premolars and the first molar were removed in the left mandible. Three months later, five implants were installed. Four implants received a fixed provisional restoration and were loaded immediately. The most anterior implant was used as unloaded control. Polychromatic fluorescence labelling was performed to assess the BMAR. After 4 months, the implants were retrieved together with the adjacent bone. Histological specimens were prepared and subjected to a fluorescence microscopic and histomorphometric analysis. Two provisional restorations were found partially lost at the end of the observation period. One implant that had lost the splinting fixation showed soft connective tissue healing. The BMAR did not differ statistically significantly between loaded and unloaded implants and within the single groups during the observation period (BMARloaded days 14−42=1.8±0.2 μm/d, BMARloaded days 42−70=1.8±0.1 μm/d, BMARloaded days 70−98=1.6±0.1 μm/d, pBMARloaded days 14–42/42–70/70–98=0.156, BMARunloaded days 14−42=1.7±0.1 μm/d, BMARunloaded days 42−70=1.8±0.2 μm/d, BMARunloaded days 70−98=1.6±0.4 μm/d, pBMARunloaded days 14–42/42–70/70–98=0.368, pBMARloaded/unloaded days 14–42=0.073, pBMARloaded/unloaded days 42–70=0.098, pBMARloaded/unloaded days 70–98=0.262). Four months after implant placement, the bone‐to‐implant contact was 77.8±17.3% for the loaded and 78.0±5.8% for the unloaded implants (P=0.753). Immediate loading does not affect the bone mineral apposition rate when compared with unloaded implants. Rigid splinting seems to be the crucial factor for implant success. Uncontrolled masticatory forces can cause failure after partial loss of the provisional restoration.
Url:
DOI: 10.1034/j.1600-0501.2003.120906.x
Affiliations:
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KölnHelmut Steveling, Department of Oral and Maxillofacial Surgery, University of Heidelberg, HeidelbergMartin Radespiel‐Tröger, Department of Medical Informatics, Biometry and Epidemiology, University of Erlangen‐Nuremberg, Erlangen</wicri:regionArea><placeName><settlement type="city">Erlangen</settlement><region type="land" nuts="1">Bavière</region><region type="district" nuts="2">District de Moyenne-Franconie</region></placeName></affiliation></author><author><name sortKey="Lehner, Bernhard" sort="Lehner, Bernhard" uniqKey="Lehner B" first="Bernhard" last="Lehner">Bernhard Lehner</name><affiliation wicri:level="3"><country xml:lang="fr">Allemagne</country><wicri:regionArea>Authors' affiliations:Emeka Nkenke, Bernhard Lehner, Konstanze Weinzierl, Friedrich Wilhelm Neukam,Department of Oral and Maxillofacial Surgery, University of Erlangen‐Nuremberg, Erlangen, GermanyUlf Thams, Department of Animal Pathology II, University of Complutense, Madrid, SpainJörg Neugebauer, Department of Oral and Maxillofacial Surgery, University of Köln, KölnHelmut Steveling, Department of Oral and Maxillofacial Surgery, University of Heidelberg, HeidelbergMartin Radespiel‐Tröger, Department of Medical Informatics, Biometry and Epidemiology, University of Erlangen‐Nuremberg, Erlangen</wicri:regionArea><placeName><settlement type="city">Erlangen</settlement><region type="land" nuts="1">Bavière</region><region type="district" nuts="2">District de Moyenne-Franconie</region></placeName></affiliation></author><author><name sortKey="Weinzierl, Konstanze" sort="Weinzierl, Konstanze" uniqKey="Weinzierl K" first="Konstanze" last="Weinzierl">Konstanze Weinzierl</name><affiliation wicri:level="3"><country xml:lang="fr">Allemagne</country><wicri:regionArea>Authors' affiliations:Emeka Nkenke, Bernhard Lehner, Konstanze Weinzierl, Friedrich Wilhelm Neukam,Department of Oral and Maxillofacial Surgery, University of Erlangen‐Nuremberg, Erlangen, GermanyUlf Thams, Department of Animal Pathology II, University of Complutense, Madrid, SpainJörg Neugebauer, Department of Oral and Maxillofacial Surgery, University of Köln, KölnHelmut Steveling, Department of Oral and Maxillofacial Surgery, University of Heidelberg, HeidelbergMartin Radespiel‐Tröger, Department of Medical Informatics, Biometry and Epidemiology, University of Erlangen‐Nuremberg, Erlangen</wicri:regionArea><placeName><settlement type="city">Erlangen</settlement><region type="land" nuts="1">Bavière</region><region type="district" nuts="2">District de Moyenne-Franconie</region></placeName></affiliation></author><author><name sortKey="Thams, Ulf" sort="Thams, Ulf" uniqKey="Thams U" first="Ulf" last="Thams">Ulf Thams</name><affiliation wicri:level="3"><country xml:lang="fr">Allemagne</country><wicri:regionArea>Authors' affiliations:Emeka Nkenke, Bernhard Lehner, Konstanze Weinzierl, Friedrich Wilhelm Neukam,Department of Oral and Maxillofacial Surgery, University of Erlangen‐Nuremberg, Erlangen, GermanyUlf Thams, Department of Animal Pathology II, University of Complutense, Madrid, SpainJörg Neugebauer, Department of Oral and Maxillofacial Surgery, University of Köln, KölnHelmut Steveling, Department of Oral and Maxillofacial Surgery, University of Heidelberg, HeidelbergMartin Radespiel‐Tröger, Department of Medical Informatics, Biometry and Epidemiology, University of Erlangen‐Nuremberg, Erlangen</wicri:regionArea><placeName><settlement type="city">Erlangen</settlement><region type="land" nuts="1">Bavière</region><region type="district" nuts="2">District de Moyenne-Franconie</region></placeName></affiliation></author><author><name sortKey="Neugebauer, Jorg" sort="Neugebauer, Jorg" uniqKey="Neugebauer J" first="Jörg" last="Neugebauer">Jörg Neugebauer</name><affiliation wicri:level="3"><country xml:lang="fr">Allemagne</country><wicri:regionArea>Authors' affiliations:Emeka Nkenke, Bernhard Lehner, Konstanze Weinzierl, Friedrich Wilhelm Neukam,Department of Oral and Maxillofacial Surgery, University of Erlangen‐Nuremberg, Erlangen, GermanyUlf Thams, Department of Animal Pathology II, University of Complutense, Madrid, SpainJörg Neugebauer, Department of Oral and Maxillofacial Surgery, University of Köln, KölnHelmut Steveling, Department of Oral and Maxillofacial Surgery, University of Heidelberg, HeidelbergMartin Radespiel‐Tröger, Department of Medical Informatics, Biometry and Epidemiology, University of Erlangen‐Nuremberg, Erlangen</wicri:regionArea><placeName><settlement type="city">Erlangen</settlement><region type="land" nuts="1">Bavière</region><region type="district" nuts="2">District de Moyenne-Franconie</region></placeName></affiliation></author><author><name sortKey="Steveling, Helmut" sort="Steveling, Helmut" uniqKey="Steveling H" first="Helmut" last="Steveling">Helmut Steveling</name><affiliation wicri:level="3"><country xml:lang="fr">Allemagne</country><wicri:regionArea>Authors' affiliations:Emeka Nkenke, Bernhard Lehner, Konstanze Weinzierl, Friedrich Wilhelm Neukam,Department of Oral and Maxillofacial Surgery, University of Erlangen‐Nuremberg, Erlangen, GermanyUlf Thams, Department of Animal Pathology II, University of Complutense, Madrid, SpainJörg Neugebauer, Department of Oral and Maxillofacial Surgery, University of Köln, KölnHelmut Steveling, Department of Oral and Maxillofacial Surgery, University of Heidelberg, HeidelbergMartin Radespiel‐Tröger, Department of Medical Informatics, Biometry and Epidemiology, University of Erlangen‐Nuremberg, Erlangen</wicri:regionArea><placeName><settlement type="city">Erlangen</settlement><region type="land" nuts="1">Bavière</region><region type="district" nuts="2">District de Moyenne-Franconie</region></placeName></affiliation></author><author><name sortKey="Radespiel Roger, Martin" sort="Radespiel Roger, Martin" uniqKey="Radespiel Roger M" first="Martin" last="Radespiel-Tröger">Martin Radespiel-Tröger</name><affiliation wicri:level="3"><country xml:lang="fr">Allemagne</country><wicri:regionArea>Authors' affiliations:Emeka Nkenke, Bernhard Lehner, Konstanze Weinzierl, Friedrich Wilhelm Neukam,Department of Oral and Maxillofacial Surgery, University of Erlangen‐Nuremberg, Erlangen, GermanyUlf Thams, Department of Animal Pathology II, University of Complutense, Madrid, SpainJörg Neugebauer, Department of Oral and Maxillofacial Surgery, University of Köln, KölnHelmut Steveling, Department of Oral and Maxillofacial Surgery, University of Heidelberg, HeidelbergMartin Radespiel‐Tröger, Department of Medical Informatics, Biometry and Epidemiology, University of Erlangen‐Nuremberg, Erlangen</wicri:regionArea><placeName><settlement type="city">Erlangen</settlement><region type="land" nuts="1">Bavière</region><region type="district" nuts="2">District de Moyenne-Franconie</region></placeName></affiliation></author><author><name sortKey="Neukam, Friedrich Wilhelm" sort="Neukam, Friedrich Wilhelm" uniqKey="Neukam F" first="Friedrich Wilhelm" last="Neukam">Friedrich Wilhelm Neukam</name><affiliation wicri:level="3"><country xml:lang="fr">Allemagne</country><wicri:regionArea>Authors' affiliations:Emeka Nkenke, Bernhard Lehner, Konstanze Weinzierl, Friedrich Wilhelm Neukam,Department of Oral and Maxillofacial Surgery, University of Erlangen‐Nuremberg, Erlangen, GermanyUlf Thams, Department of Animal Pathology II, University of Complutense, Madrid, SpainJörg Neugebauer, Department of Oral and Maxillofacial Surgery, University of Köln, KölnHelmut Steveling, Department of Oral and Maxillofacial Surgery, University of Heidelberg, HeidelbergMartin Radespiel‐Tröger, Department of Medical Informatics, Biometry and Epidemiology, University of Erlangen‐Nuremberg, Erlangen</wicri:regionArea><placeName><settlement type="city">Erlangen</settlement><region type="land" nuts="1">Bavière</region><region type="district" nuts="2">District de Moyenne-Franconie</region></placeName></affiliation></author></analytic><monogr></monogr><series><title level="j" type="main">Clinical Oral Implants Research</title><title level="j" type="alt">CLINICAL ORAL IMPLANTS RESEARCH</title><idno type="ISSN">0905-7161</idno><idno type="eISSN">1600-0501</idno><imprint><biblScope unit="vol">14</biblScope><biblScope unit="issue">3</biblScope><biblScope unit="page" from="312">312</biblScope><biblScope unit="page" to="321">321</biblScope><biblScope unit="page-count">10</biblScope><publisher>Munksgaard International Publishers</publisher><pubPlace>Oxford, UK</pubPlace><date type="published" when="2003-05">2003-05</date></imprint><idno type="ISSN">0905-7161</idno></series></biblStruct></sourceDesc><seriesStmt><idno type="ISSN">0905-7161</idno></seriesStmt></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Animals</term><term>Apical thread</term><term>Apposition</term><term>Beagle dogs</term><term>Bmar</term><term>Bmar jours</term><term>Body weight</term><term>Bone Density (physiology)</term><term>Bone area</term><term>Bone density</term><term>Bone formation</term><term>Bone growth</term><term>Bone mineral apposition rate</term><term>Bone remodelling</term><term>Brunski</term><term>Calcification, Physiologic (physiology)</term><term>Cargados</term><term>Case reports</term><term>Clin</term><term>Current literature</term><term>Days bmar</term><term>Days pbmar</term><term>Dental Implants</term><term>Dental Prosthesis, Implant-Supported</term><term>Dental Restoration Failure</term><term>Dental implantology</term><term>Dental implants</term><term>Dentistry</term><term>Denture, Partial, Fixed</term><term>Denture, Partial, Temporary</term><term>Edentulous</term><term>Edentulous mandible</term><term>Experimental animal trials</term><term>Fluorescent Dyes</term><term>Friadent gmbh</term><term>General anaesthesia</term><term>Gmbh</term><term>Healing period</term><term>Histological</term><term>Histomorphometric</term><term>Histomorphometric analysis</term><term>Immediate loading</term><term>Impl</term><term>Implant</term><term>Implant placement</term><term>Implant success</term><term>Implantes</term><term>Implants research</term><term>International journal</term><term>Interthread bone area</term><term>Jaw, Edentulous, Partially (pathology)</term><term>Jaw, Edentulous, Partially (surgery)</term><term>Jours</term><term>Mandible</term><term>Mandible (pathology)</term><term>Maxillofacial</term><term>Maxillofacial implants</term><term>Maxillofacial surgery</term><term>Mini</term><term>Mini pigs</term><term>Nemark</term><term>Nemark implants</term><term>Nkenke</term><term>Observation period</term><term>Oral impl</term><term>Osseointegration</term><term>Osteogenesis (physiology)</term><term>Pbmar</term><term>Periodontology</term><term>Piattelli</term><term>Placement torque value</term><term>Present study</term><term>Primary stability</term><term>Prosthetic dentistry</term><term>Provisional restoration</term><term>Provisional restorations</term><term>Remodelling</term><term>Restorative dentistry</term><term>Rigid splinting</term><term>Rztliche implantologie</term><term>Screw implants</term><term>Splinting</term><term>Statistics, Nonparametric</term><term>Surface Properties</term><term>Swine</term><term>Swine, Miniature</term><term>Temporary abutment caps</term><term>Titanium</term><term>Titanium implants</term><term>Uncontrolled masticatory forces</term><term>Uorescence</term><term>Uorescence labelling</term><term>Uorescent dyes</term><term>Weight-Bearing</term><term>Wound Healing</term><term>Zeiss gmbh</term><term>Zubery</term></keywords><keywords scheme="KwdFr" xml:lang="fr"><term>Animaux</term><term>Calcification physiologique (physiologie)</term><term>Cicatrisation de plaie</term><term>Colorants fluorescents</term><term>Densité osseuse (physiologie)</term><term>Implants dentaires</term><term>Mandibule (anatomopathologie)</term><term>Mise en charge</term><term>Mâchoire partiellement édentée ()</term><term>Mâchoire partiellement édentée (anatomopathologie)</term><term>Ostéo-intégration</term><term>Ostéogenèse (physiologie)</term><term>Porc miniature</term><term>Propriétés de surface</term><term>Prothèse dentaire implanto-portée</term><term>Prothèse dentaire partielle provisoire</term><term>Prothèse partielle fixe</term><term>Statistique non paramétrique</term><term>Suidae</term><term>Échec de restauration dentaire</term></keywords><keywords scheme="MESH" type="chemical" xml:lang="en"><term>Dental Implants</term><term>Fluorescent Dyes</term></keywords><keywords scheme="MESH" qualifier="anatomopathologie" xml:lang="fr"><term>Mandibule</term><term>Mâchoire partiellement édentée</term></keywords><keywords scheme="MESH" qualifier="pathology" xml:lang="en"><term>Jaw, Edentulous, Partially</term><term>Mandible</term></keywords><keywords scheme="MESH" qualifier="physiologie" xml:lang="fr"><term>Calcification physiologique</term><term>Densité osseuse</term><term>Ostéogenèse</term></keywords><keywords scheme="MESH" qualifier="physiology" xml:lang="en"><term>Bone Density</term><term>Calcification, Physiologic</term><term>Osteogenesis</term></keywords><keywords scheme="MESH" qualifier="surgery" xml:lang="en"><term>Jaw, Edentulous, Partially</term></keywords><keywords scheme="Teeft" xml:lang="en"><term>Animals</term><term>Apical thread</term><term>Apposition</term><term>Beagle dogs</term><term>Bmar</term><term>Bmar jours</term><term>Body weight</term><term>Bone area</term><term>Bone density</term><term>Bone formation</term><term>Bone growth</term><term>Bone mineral apposition rate</term><term>Bone remodelling</term><term>Brunski</term><term>Cargados</term><term>Case reports</term><term>Clin</term><term>Current literature</term><term>Days bmar</term><term>Days pbmar</term><term>Dental Prosthesis, Implant-Supported</term><term>Dental Restoration Failure</term><term>Dental implantology</term><term>Dental implants</term><term>Dentistry</term><term>Denture, Partial, Fixed</term><term>Denture, Partial, Temporary</term><term>Edentulous</term><term>Edentulous mandible</term><term>Experimental animal trials</term><term>Friadent gmbh</term><term>General anaesthesia</term><term>Gmbh</term><term>Healing period</term><term>Histological</term><term>Histomorphometric</term><term>Histomorphometric analysis</term><term>Immediate loading</term><term>Impl</term><term>Implant</term><term>Implant placement</term><term>Implant success</term><term>Implantes</term><term>Implants research</term><term>International journal</term><term>Interthread bone area</term><term>Jours</term><term>Mandible</term><term>Maxillofacial</term><term>Maxillofacial implants</term><term>Maxillofacial surgery</term><term>Mini</term><term>Mini pigs</term><term>Nemark</term><term>Nemark implants</term><term>Nkenke</term><term>Observation period</term><term>Oral impl</term><term>Osseointegration</term><term>Pbmar</term><term>Periodontology</term><term>Piattelli</term><term>Placement torque value</term><term>Present study</term><term>Primary stability</term><term>Prosthetic dentistry</term><term>Provisional restoration</term><term>Provisional restorations</term><term>Remodelling</term><term>Restorative dentistry</term><term>Rigid splinting</term><term>Rztliche implantologie</term><term>Screw implants</term><term>Splinting</term><term>Statistics, Nonparametric</term><term>Surface Properties</term><term>Swine</term><term>Swine, Miniature</term><term>Temporary abutment caps</term><term>Titanium</term><term>Titanium implants</term><term>Uncontrolled masticatory forces</term><term>Uorescence</term><term>Uorescence labelling</term><term>Uorescent dyes</term><term>Weight-Bearing</term><term>Wound Healing</term><term>Zeiss gmbh</term><term>Zubery</term></keywords><keywords scheme="Wicri" type="topic" xml:lang="fr"><term>Animaux</term><term>Cicatrisation de plaie</term><term>Colorants fluorescents</term><term>Implants dentaires</term><term>Mise en charge</term><term>Mâchoire partiellement édentée</term><term>Ostéo-intégration</term><term>Porc miniature</term><term>Propriétés de surface</term><term>Prothèse dentaire implanto-portée</term><term>Prothèse dentaire partielle provisoire</term><term>Prothèse partielle fixe</term><term>Statistique non paramétrique</term><term>Suidae</term><term>Titane</term><term>Échec de restauration dentaire</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract">Abstract: The aim of the study was to compare the bone mineral apposition rate (BMAR) of immediately loaded implants with an unloaded control during the early healing phase in the partially edentulous mandible. In seven mini pigs, three premolars and the first molar were removed in the left mandible. Three months later, five implants were installed. Four implants received a fixed provisional restoration and were loaded immediately. The most anterior implant was used as unloaded control. Polychromatic fluorescence labelling was performed to assess the BMAR. After 4 months, the implants were retrieved together with the adjacent bone. Histological specimens were prepared and subjected to a fluorescence microscopic and histomorphometric analysis. Two provisional restorations were found partially lost at the end of the observation period. One implant that had lost the splinting fixation showed soft connective tissue healing. The BMAR did not differ statistically significantly between loaded and unloaded implants and within the single groups during the observation period (BMARloaded days 14−42=1.8±0.2 μm/d, BMARloaded days 42−70=1.8±0.1 μm/d, BMARloaded days 70−98=1.6±0.1 μm/d, pBMARloaded days 14–42/42–70/70–98=0.156, BMARunloaded days 14−42=1.7±0.1 μm/d, BMARunloaded days 42−70=1.8±0.2 μm/d, BMARunloaded days 70−98=1.6±0.4 μm/d, pBMARunloaded days 14–42/42–70/70–98=0.368, pBMARloaded/unloaded days 14–42=0.073, pBMARloaded/unloaded days 42–70=0.098, pBMARloaded/unloaded days 70–98=0.262). Four months after implant placement, the bone‐to‐implant contact was 77.8±17.3% for the loaded and 78.0±5.8% for the unloaded implants (P=0.753). Immediate loading does not affect the bone mineral apposition rate when compared with unloaded implants. Rigid splinting seems to be the crucial factor for implant success. Uncontrolled masticatory forces can cause failure after partial loss of the provisional restoration.</div></front></TEI><affiliations><list><country><li>Allemagne</li></country><region><li>Bavière</li><li>District de Moyenne-Franconie</li></region><settlement><li>Erlangen</li></settlement></list><tree><country name="Allemagne"><region name="Bavière"><name sortKey="Nkenke, Emeka" sort="Nkenke, Emeka" uniqKey="Nkenke E" first="Emeka" last="Nkenke">Emeka Nkenke</name></region><name sortKey="Lehner, Bernhard" sort="Lehner, Bernhard" uniqKey="Lehner B" first="Bernhard" last="Lehner">Bernhard Lehner</name><name sortKey="Neugebauer, Jorg" sort="Neugebauer, Jorg" uniqKey="Neugebauer J" first="Jörg" last="Neugebauer">Jörg Neugebauer</name><name sortKey="Neukam, Friedrich Wilhelm" sort="Neukam, Friedrich Wilhelm" uniqKey="Neukam F" first="Friedrich Wilhelm" last="Neukam">Friedrich Wilhelm Neukam</name><name sortKey="Radespiel Roger, Martin" sort="Radespiel Roger, Martin" uniqKey="Radespiel Roger M" first="Martin" last="Radespiel-Tröger">Martin Radespiel-Tröger</name><name sortKey="Steveling, Helmut" sort="Steveling, Helmut" uniqKey="Steveling H" first="Helmut" last="Steveling">Helmut Steveling</name><name sortKey="Thams, Ulf" sort="Thams, Ulf" uniqKey="Thams U" first="Ulf" last="Thams">Ulf Thams</name><name sortKey="Weinzierl, Konstanze" sort="Weinzierl, Konstanze" uniqKey="Weinzierl K" first="Konstanze" last="Weinzierl">Konstanze Weinzierl</name></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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